Polynucleotides: Salmon DNA treatment
The Salmon DNA treatment, also known as the salmon sperm treatment or polynucleotide skin booster (PDRN), Is an innovative injectable which it self-healing power of the skin activates. This natural booster stimulates cell renewal, collagen building and deep hydration in the skin. The result: fresh, firm skin with a healthy glow, While maintaining a natural appearanceraling.
On this page, you will find all the information about treatment with polynucleotides.
What is a salmon DNA treatment?
In this treatment, we use so called polynucleotides. These are natural DNA fragments that are mostly extracted from salmon, because of its strong DNA. This excerpts Have a powerful regenerative effect on the skin: they stimulate namely Cell growth, improve blood flow of the skin (and thus its ability to recover) èn Promote the production of collagen and elastin For improving fine lines, wrinkles and firmness.
Main effects of polynucleotide skin booster:
- Skin Repair and Renewal: Supports the natural healing process
- Deep hydration: Reduces dry lines and improves skin quality
- Increased firmness and elasticity: gives the skin a lifting effect
- Reduced redness and irritation: Works to soothe and strengthen the skin barrier
Plenhyage XL - The high-performance Polynucleotide Skinbooster
At DokterEs , we work with Plenhyage XL, an advanced polynucleotide skin booster sourced from BIOFORMULA. Because of its ideal purity, long-lasting hydration, and scavenge activity against free radicals, Plenhyage XL stimulates collagen and elastin production at the cellular level.
Scientific foundation
The action of Plenhyage XL is based on PN-HPTâ„¢ technology, for which clinical and preclinical data are available: after 20 weeks of observation, patients noted up to +115% skin hydration and +38% elasticity, with also positive results in skin repair and collagen synthesis in animal studies.
(Source: DermaFocus, Medifine Skin Clinic)
Salmon DNA or salmon sperm treatment: what's the difference?
Online, you often see the term "salmon sperm treatment" front. This is actually the same as the salmon DNA treatment: namely, the DNA fragments are extracted from salmon sperm cells and then thoroughly purified. So you obviously don't get pure salmon sperm cells injected.
In the medical world, therefore, we prefer to use the terms salmon DNA treatment, polynucleotide skin booster or PDRN, as this more clearly and correctly describes the effect and application.
result
The steps of a polynucleotide treatment
A salmon DNA or polynucleotide treatment follows a clear step-by-step plan:
During the consultation, we look at your skin and discuss whether treatment with polynucleotides is the right choice for your needs. A combination with other (injectable) treatments is often also an option.
The skin is cleansed, after which we apply polynucleotides to the skin with small injections. This can be done, for example, in the face, neck or décolleté. The treatment is quick and usually not painful.
The doctor clearly discusses all aftercare instructions. You will also receive these by mail after the appointment. You do not have to stay out of the sun. However, it is important to protect your face with an SPF50 when you go out in the sun.
There may be slight redness or swelling or a blue spot that disappears within a few days. Blue spots may be camouflaged with makeup.
Physical exertion or connective tissue massages need not be avoided. Thus, exercising is allowed.
After a few sessions, you'll see fresher, smoother skin with improved elasticity.
before and after results salmon dna treatment
The results of the salmon DNA treatment Builds up gradually in the weeks following treatment. The skin becomes:
- Visibly firmer and more elastic
- Better hydrated and more even
- Fresher and more youthful appearance
For best results, we recommend on average 2-3 sessions, After which maintenance treatments every 6-12 months are sufficient to maintain results.

curious what we can do for you?
We are ready to advise and support you in achieving your skin goals. Feel free to contact us for a personal consultation and answers to all your questions.
Frequently Asked Questions
We understand that you may still have questions. Feel free to give us a call or read the questions we get frequently below.
Salmon DNA treatment involves the use of a skin-enhancing injectable With polynucleotides, which cell renewal stimulates and improves the skin from the inside out. Therefore, it is not the same as botox (muscle relaxant) or fillers (Volume restoration through filling with hyaluronic acid).
Yes, both terms refer to the same treatment. Medically, we call this a polynucleotide skin booster (PDRN). The substances used in this treatment are extracted from the DNA of salmon sperm, but no pure salmon sperm is injected.
An average of 2-3 sessions for optimal results, thereafter is 1 maintenance treatment every 6-12 months featured.
Yes, side effects are minimal. You may experience slight redness or swelling, but this usually disappears within a few hours.
The price is €350 per session.
Restore your skin from within with a Polynucleotides (Salmon DNA) treatment
Skin aging, sagging or dull skin doesn't have to hinder your self-confidence. With a Polynucleotides treatment (also known as Salmon DNA treatment) at DokterEs , you naturally stimulate your skin's cell renewal, collagen production and hydration. The result? A firmer, smoother and fresher appearance - without looking "treated."
Want to know if a Polynucleotide treatment is right for your skin? Schedule a complimentary consultation with our specialists today and discover the power of regenerative skin improvement.
the power of combination
Polynucleotide treatment can be combined well with other skin improvement treatments. Whereas salmon DNA provides a beautiful glow and improves skin condition, other injectables treatments such as botox and hyaluronic acid fillers focus more on reducing deep, dynamic and static wrinkles and restoring volume loss. Microneedling, microbotox, peels, laser treatments and the use of proper skincare are also a good foundation for maintaining beautiful skin.
Wondering if Salmon DNA is right for you? Schedule a consultation!
Want to know if treatment with Polynucleotides suits your skin needs and expectations? During a free consultation, we discuss your needs and draw up a personal treatment plan. We give you transparent explanations about the treatment, the procedure, costs and possible alternatives.
Our Skin Improvement Treatments
Why clients choose DokterEs in Eindhoven
Why do people choose a skin-enhancing treatment at DokterEs? Our approach is based on safety, expertise, honest advice, and personal care.What sets us apart:
- Experienced professionals with extensive experience with biostimulators and skin boosters and a broad view of skin improvement.
- Excellent Google reviews:On average, we score 5/5 stars based on more than 90 reviews.
- Treatments with a focus on natural results: aimed at obtaining and maintaining a healthy skin texture and highlighting your own beauty.
- Personalized treatment plan: nostandard treatments, but customization for each person's individual beauty.We truly take the time to create a customized plan that meets your personal needs.
- Safe and reliable:Use of premium and A-brand products in a professional environment where honesty and transparency are key.
- Modern clinic:A luxurious environment where you will feel right at home.
- Total Concept with everything under one roof: In addition to skin improvement, we offer a total concept that includes fillers, botox, skincare, and minor surgery so that we can fully customize your treatment plan to your needs and desires.
- DokterEs has been around since 2017 and has become a reputable clinic with an excellent reputation for safe and expert skin improvement.
Learn more about skin enhancement at dokteres?
Want to learn more about our vision for skin improvement and how we work together to build beautiful, firm and healthy skin?
Then check out our skin enhancement page here and discover how we use a variety of techniques to improve and maintain skin quality.