Medical weight loss with injections
Lose weight responsibly with injections under direct physician supervision. The body's own hormone (GLP-1) helps regulate your appetite. Less hunger, faster fullness and more peace of mind in your eating behavior, so that healthy choices become feasible again and weight loss finally succeeds. Our common goal? Sustainable weight loss and health gains.
At DokterEs in Eindhoven, you never do this alone: we combine medication with a personal lifestyle plan and regular check-ins.
- Safe, transparent, and focused on lasting results.
- Approachable WhatsApp contact with 24/7 accessibility
- Lowest effective dose
What is medical weight loss with injections?
Medical weight loss with injections is targeted weight loss using proven medication (GLP-1 receptor agonists such as Wegovy, Ozempic, Saxenda and Mounjaro) combined with lifestyle coaching. Your course with us runs under the supervision of a doctor and with a counselor as your permanent contact.
How do GLP-1 injections work?
GLP-1 is a body's own intestinal hormone that regulates satiety and blood sugar, among other things, after a meal; the medication enhances this natural process. The injection "turns up the satiety knob" slightly, slows gastric emptying. Result: less hunger, more often full and more stable energy. This makes healthier eating of smaller portions much easier to maintain.
Effects on appetite, metabolism and hormones
- Reduced hunger and snack cravings
- Slower gastric emptying → faster feeling of fullness
- Better hormone balance
- Weight loss between ~10-22% after 1-1.5 years (medium and dose dependent).
why choose dokteres?
At DokterEs , you choose a physician-led course with real attention. We translate your story into a customized plan: lifestyle always central-and keep the lines short via WhatsApp with your regular practitioners. We make losing weight safe, understandable and achievable, with an eye for both your health and your appearance.
"If losing weight keeps 'failing,' it's not a lack of willpower-it's often biology. With the right indication, gentle build-up and a team that thinks with you, losing weight becomes attainable and sustainable again."
why choose dokteres?
Previous pancreatitis
Severe active gastrointestinal diseases
(Personal or familial) medullary thyroid carcinoma (MTC) or MEN2
Allergy to the drug or excipients
Pregnancy or breastfeeding
Allergy to the drug or excipients
Who is medical weight loss with injections for?
Medical weight loss with GLP-1 injections is for adults who are struggling to sustainably lose weight on their own or maintain the weight loss achieved.
At DokterEs , we personally review each situation: your goals, health, medical history, medications, and lifestyle. Based on this, the doctor assesses whether it is safe to start medication that will help with weight loss.
How do we determine if GLP-1 injections are right for you?
In an initial consultation, we take extensive time. We ask about your health (illnesses, medications, allergies), your wishes and goals, lifestyle (food, exercise, sleep, stress), previous weight loss attempts and what did and did not work. On this basis, the doctor assesses whether starting is sensible and safe.
GLP-1 medication is safe provided you use it correctly indicated, built up slowly, and under medical supervision. We always screen for situations in which you should not (yet) start, such as pregnancy/childbearing wish and breastfeeding, previous pancreatitis, MEN2/MTC in the family, severe active gastrointestinal problems or other obvious contraindications. Only when the doctor gives the green light, we start, always together with lifestyle advice.
Did you know!
Dietician Netty van Kaathoven and physician Esther de Vries co-wrote the book Zo blijf je sterk en in balans tijdens en na GLP-1. A practical and up-to-date book for anyone taking or considering GLP-1 medication, focusing on healthy weight loss, muscle maintenance and sustainable lifestyle changes.
You will receive the book when you start your journey at DokterEs!
The book is not just about losing weight, but mostly about becoming stronger, healthier and more balanced, during and after GLP-1. In the book you will read, among other things, how to get enough protein and fiber, why exercise is important, how to deal with less hunger and cravings, and how to build an eating pattern that is sustainable in the long term.
From her experience as a physician within GLP-1 pathways, Esther provided medical input on how GLP-1 works, appropriate dosage, possible side effects, metabolic health, hormonal recovery, and the importance of proper counseling.
Why lose weight with injections at DokterEs in Eindhoven
Why do people choose medically supervised weight loss with injections at DokterEs? We have a highly committed team that guides you step by step, under the direct supervision of a doctor with exceptional expertise. Our approach is based on safety, expertise and personalized care. What sets us apart:
- Personal attention and short lines: customized, no standard protocol. Direct WhatsApp contact with your consultant, including evenings and weekends. Regular check ins and quick adjustments.
- Exceptional expertise Dr. Dianne van Beek: physician, epidemiologist, PhD, background in clinical pharmacology and extensive practical experience with semaglutide and tirzepatide. She translates new studies into a personalized and safe plan.
- Physician-led care from intake to outcome: each course is designed and monitored by our physicians.
- Lifestyle plus medication: GLP 1 injections combined with diet, exercise, sleep and behavior. If desired, we will pair you with gym or personal trainer.
- Total package without fuss: clear path with consultations, coaching and monitoring. Rate €399 per month including semaglutide.
- Attention to your appearance while losing weight: advice for maintaining skin quality and volume. If desired, we create a treatment plan for preventing skin laxity and facial volume loss with natural skin boosters, subtle fillers, biostimulation, or lipofilling at the right time.
- Long-term strategy: of course we want you to lose weight, but even more important to us is your success in maintaining your target weight. We understand what it takes to achieve this and provide intensive support.
How do we ensure success?
At DokterEs , medical weight loss is always a guided journey. We start safely, build up slowly, choose the lowest effective dose and link this to lifestyle coaching. This way you increase the chances of results and retention.
here's how we approach it
Custom titration & dosing: we increase to the lowest effective dose only when necessary and actively manage side effects.
Muscle mass & energy consumption: strength training and adequate protein increase resting metabolism, so you can eat more after stopping without gaining weight.
Retention: at least 3 months of consolidation at the lowest effective dose; during this time, new habits wear in.
Tapering plan: complete tapering where possible, maintenance dosing where necessary; with relapse prevention and aftercare.
Collaborations: we pair you with a gym or personal trainer with a shared vision, for lasting results, upon request.
curious what we can do for you?
Want to know if GLP-1 injections are right for you and how we safely combine it with lifestyle counseling? Schedule a no-obligation consultation with DokterEs. We'll do a quick suitability check, answer all your questions and create a personalized plan tailored to your needs.
how does the process work?
The treatment process at DokterEs
Our approach is based on safety, expertise, and personal care. Each course is supervised by our physician with exceptional expertise Dr. Dianne van BeekL physician, epidemiologist, PhD, background in clinical pharmacology and extensive practical experience with semaglutide and tirzepatide. She translates your story into a personalized and safe plan.
This process includes at least 6 months of intensive counseling to ensure that you achieve and maintain your goals.
A brief introduction at the clinic or through a video appointment where you can ask all your questions and we will explore with you if this course of treatment suits you and is right for you.
We listen to your story and assess your health.
Intake interview: goals, previous attempts, eating and exercise habits, sleep and stress.
Measurements: weight, BMI, waist circumference and blood pressure.
Medication and contraindication check
Explanation of effects, expectations, side effects, and lifestyle approaches.
Personalized plan: choice of GLP-1 agent and titration schedule, lifestyle guidelines, and monitoring arrangements.
- Advice for maintaining skin quality and volume. If desired, we create a treatment plan for preventing skin laxity and facial volume loss with natural skin boosters, subtle fillers, biostimulation, or lipofilling at the appropriate time.
You start with medication and weight loss under supervision. You will receive your medication at home through our online pharmacy.
If desired, we will put the initial injection together at the clinic.
You start with:
Dosage and accrual according to plan; timely check-ins (WhatsApp/phone/consultation).
Coaching on nutrition, protein intake, exercise, muscle mass, sleep and behavior; linkage with gym or personal trainer possible.
Side effect management and pace/dosage adjustments as needed.
We increase step by step to the lowest effective dosage possible: enough "wind at your back" to meet your goals, but as low as possible so that tapering off is easier later. We monitor weight, hunger, satiety and well-being and make adjustments as needed.
We also build on advice around a lifestyle with a higher resting metabolism = more energy consumption at rest. This allows you to eat a little more without gaining weight and makes it easier to maintain your target weight later.
After achieving your goal, we keep the weight stable for 3 months with medication. In this phase, you continue to build your new routine: eat less but more nutritiously, exercise more, sleep better, deal with temptations. We stay on the lowest effective dose so that your lifestyle change is increasingly on its own.
Intensive supervision is crucial during the phasing out process; we pay attention to hunger and relapse signals and adjust lifestyle or dosage temporarily. Most people are successful in phasing out, provided that the lifestyle changes are really ingrained.
We guide you to stable weight maintenance and realistic follow-up. A part can stop completely: because the lifestyle is successfully changed and also the resting metabolism is higher. Some need a small long-term maintenance dose. If necessary, we discuss a (lower) maintenance dose to maintain weight.
Plan for tapering, maintenance dosage or long-term use - always personalized and safe.
Relapse prevention: routines, exercise goals and relapse strategy.
GLP-1 slimming medication overview.
We use only proven remedies and choose customized treatments based on your situation.
Safety and side effects
GLP-1 injections are safe when properly indicated, carefully constructed, and properly monitored. Below you can read about what to expect and what side effects may occur. These are usually temporary in nature and usually subside within a few weeks. The dosage will be adjusted in case of any side effects.
Losing weight safely starts with a good indication, building up slowly and monitoring closely. I would rather choose a lower start and tight monitoring than quick steps. This way, losing weight becomes safe and maintainable.
Common side effects
Why GLP-1 injections are safe
curious what we can do for you?
We are ready to advise and support you in achieving your weight and lifestyle goals. Feel free to contact us for a personal consultation and answers to all your questions.
why lose weight with injections?
Losing weight is extremely difficult for many people , not because of a lack of willpower, but because of biology, hormones, medication or lifestyle. At the same time, it is crucial to your health and daily well-being. GLP-1 injections are a tool, not a quick fix: they dampen hunger and snack cravings, making healthy choices and exercise feel achievable again. At DokterEs , we always combine this with personal coaching, a gentle build-up schedule and physician oversight, so that you not only achieve results, but maintain them.
"Achieving and maintaining a healthy weight is crucial to your health and daily well-being. we are committed to helping you achieve and maintain your target weight."
what does weight loss provide?
how do we maintain results?
Frequently Asked Questions
We understand that you may still have questions. Feel free to give us a call or read the questions we get frequently below.
Totally understandable question, as there is a lot on social media and the Internet that GLP-1 agents could be harmful. There are always risks associated with the use of medication. However, these are very limited with GLP-1 medications and having oversight has more health risks than using them.
Here's how we ensure safety and why, with the right patient, the benefits often outweigh the risks:
Contraindications screening. We exclude pregnancy/childhood wish, previous pancreatitis, and (familial) MEN2/MTC, among others, and review your medication list carefully.
Quiet titration + monitoring. We build up step by step and track weight, blood pressure, symptoms, and lab values as needed.
Side effects usually mild and temporary. Consider nausea, feeling full, belching, constipation/diarrhea or abdominal pain in the first few weeks-usually go away with slower accrual or temporary withdrawal.
Clear "sick-day rules" and 24/7 accessibility. In case of persistent vomiting, severe abdominal pain, or other alarm symptoms, switch with us immediately.
In addition, you should realize that:
Obesity itself increases the risk of cardiovascular disease, type-2 diabetes, high blood pressure, stroke, sleep apnea, liver disease/NAFLD, joint disease and various cancers, among others. This is well documented by CDC/WHO and the NIDDK.
Demonstrated risk reduction with GLP-1 in the right target population.
In people with overweight/obese and existing cardiovascular disease, semaglutide 2.4 mg reduced the risk of cardiovascular death, non-fatal infarction or stroke by ~20% (SELECT study).
GLP-1s on average lower systolic blood pressure (order of a few mmHg), providing additional cardioprotection.
Tirzepatide (Zepbound) showed marked improvement in the Apnea-Hypopnea Index in people with obesity and obstructive sleep apnea and received FDA approval.
Weight loss is the driving force. With GLP-1s, when used correctly, we often see double-digit weight loss, which impacts glucose, blood pressure, lipids and liver fat-and thus long-term health.
In summary: GLP-1 injections are not a "quick fix," but a medical device with proven health benefits when used wisely. We provide the selection, explanation, slow build-up and guidance; you provide the lifestyle. Together, we make it safe and effective.
- On-label: according to official registration
- Obesity: BMI ≥ 30
BMI ≥ 27 and at least one weight-related condition, such as:
hypertension
elevated cholesterol or fats in the blood
(pre)diabetes or insulin resistance
sleep apnea (OSAS)
Cardiovascular disease (e.g., past heart attack or stroke)
- Off-label - customization outside the official criteria
Do you not fall exactly within the above frameworks, but after careful evaluation, the doctor expects the benefitsto outweigh the risks and there are no contraindications? Then the drug can be used off-label. This comes into play, for example, in the case of:
Persistent yo-yo weight or repeated failure of other methods
weight gain around menopause
PCOS with appetite/weight problems
joint problems due to obesity
medication-related weight gain
Short answer: an average of 8-22% of your starting weight when using GLP-1 (and GLP-1/GIP) with lifestyle guidance and proper dosing. The exact outcome varies from person to person.
Bandwidths by agent (based on large studies):
Semaglutide (weekly injection).: average ±10–15% at 12-18 months.
Tirzepatide (weekly injection, GLP-1 + GIP): average ±15–22% at 12-18 months.
Liraglutide (daily injection): average ±5–8% at 6-12 months.
Sample calculation
Starting weight 95 kg
10% = 9.5 kg
15% = 14.3 kg
20% = 19 kg
Timeline (forecast)
0-3 months: less appetite, first marked decrease.
3-6 months: often the greatest reduction.
12-18 months: effect stabilizes; then focus on maintenance (possibly maintenance dose).
What determines your outcome?
Dosage and gentle buildup (tolerance/side effects).
Lifestyle: adequate protein/fiber, exercise, sleep & structure.
Medications/hormones that affect weight (e.g., menopause, antidepressants, corticosteroids).
Starting BMI, age, comorbidities and consistency.
The choice is customized. In general, we see:
Tirzepatide (Mounjaro/Zepbound) - often the most potent in terms of weight loss (± 15-22% with proper buildup).
Semaglutide (Wegovy/Ozempic) – high weight loss (± 10-17%).
Liraglutide (Saxenda) - moderate weight loss (± 5-8%).
Effect varies from person to person and depends on purpose, side effects, history, availability and cost. We recommend which remedy and dosage is right for you.
At DokterEs we work with a total package of €399 per month, including semaglutide (if medically appropriate), consultations, coaching and monitoring. Other remedies may vary in price; we discuss that in advance. Health insurance companies do not reimburse this.
GLP-1 medication starts working as early as one day after injection. You will immediately notice that your sense of hunger decreases and you feel full faster.
You often notice weight loss within 1-2 weeks.
The greatest decrease usually occurs in months 3-6.
On average, you'll see double-digit weight loss over several months, but it remains individual.
Plateaus come with it; we then adjust dosage and lifestyle. The program lasts a minimum of 6 months for a safe and lasting effect.
Heart & Vascular
Drop in blood pressure
Improvement of cholesterol profile (↓ triglycerides; often slightly ↑ HDL).
Large outcome studies show that semaglutide can lower the risk of cardiovascular problems (heart attack/stroke/mortality) in overweight/obese people; GLP-1 drugs have long had a proven cardiovascular benefit in diabetes.
Sugar metabolism
Improvement of insulin sensitivity and HbA1c.
With pre-diabetes, much of it goes back to normal glucoses; with diabetes, medication requirements may decrease (sometimes tapering of oral agents/insulin, always under physician care).
Liver (NAFLD/NASH)
Decrease in liver fat and liver enzymes; in studies, in some Inflammatory fatty liver disease (NASH) put to rest come.
Sleep apnea
Marked decrease in apnea severity (AHI) due to weight loss; specific results for this have been published for tirzepatide. Some patients require less CPAP pressure (sleep doctor's assessment).
Kidneys
Reduced albuminuria and - in people with diabetes and kidney damage - evidence of inhibition of kidney damage progression.
Hormones & reproduction
For PCOS: more frequent regular cycles/ovulation and higher chances of pregnancy due to weight loss and improved insulin sensitivity (evidence growing, not in everyone).
Inflammation & metabolic markers
Decrease in CRP and other inflammatory markers; beneficial effects on fat distribution (↓ visceral fat).
Movement & joints
Reduced knee/hip pain and improved mobility due to reduced mechanical strain; quality of life often increases.
Drug de-escalation (selective, supervised)
In some, after improving values, blood pressure/lipid/glucose medication can be reduced or adjusted (never do it yourself; always consult with your doctor).
Important: The magnitude of effect varies from person to person and depends on consistency in lifestyle, dosage, treatment duration and medical history. GLP-1 is not a "quick fix," but a tool within a medical and lifestyle program.
Losing weight with GLP-1 injections is safe if under medical supervision. Of course, as with any medication, there are risks with use. With GLP-1 medication, apart from gastrointestinal symptoms, the following (serious) side effects have been described.
- Gallstones/gallbladder inflammation - sometimes (±1-2%)
- Pancreatitis (pancreatitis) - rare (<0.3%)
- Exacerbation of diabetic retinopathy - rare (0.01-0.1%) and especially in diabetes with rapid HbA1c decline.
- Allergic reaction - Rare - very rare (<0.1%)
- Thyroid warning (C cell tumors) - seen theoretically In rats; not demonstrated in humans.
GLP-1 medication helps change habits, giving you a chance to build a new routine and a healthy lifestyle. This contributes to lasting results. Gaining weight can happen if you stop abruptly or without a plan. Therefore:
We taper off under supervision (or choose maintenance/microdosing where appropriate).
We anchor lifestyle (protein, strength training, sleep, stress).
We offer aftercare and check-ins so you can stay on track.
This increases your chances of lasting results.
Short answer: no, you don't have to go on a heavy diet and yes, you can eat basically anything, but what and how you eat determines how well it works. We work towards an achievable lifestyle that you can maintain for a long time. For most people, that includes the occasional alcoholic beverage and something unhealthy to eat.
Our guideline in brief
No crash diet. We work with normal portions and set meal times.
80/20 principle. 80% nutritious (vegetables, fruits, whole grains, legumes, fish/chicken/egg/dairy/plant protein, nuts), 20% is flexible.
Every meal protein + fiber. Think cottage cheese/yogurt, eggs, legumes, tofu, chicken/fish + vegetables/grains. This will prevent muscle loss and keep you full longer.
Smaller, calmer meals. GLP-1 slows gastric emptying; large fatty meals can cause nausea-rather small and quiet meals.
Drink well. Guideline ~1.5-2 liters of water/tea per day.
Summary
You don't have to "ban" anything, but consistent, nutritious choices + smaller portions make all the difference. GLP-1 injections help you make these choices and develop and maintain a healthy lifestyle with a healthy weight.
Team of specialists
Want to know if GLP-1 injections are right for you and how we safely combine it with lifestyle counseling? Schedule a no-obligation consultation with DokterEs. We do a quick suitability check, answer all your questions and create a personalized plan. If desired, we will take the first injection together in the clinic and keep a close eye on your course.
